Rockefeller University

The Rockefeller University dataset includes anatomical, field map, and fMRI data from 6 monkeys.

Usage Agreement

Creative Commons – Attribution-NonCommercial Share Alike (CC-BY-NC-SA)- Standard INDI data sharing policy. Prohibits use of the data for commercial purposes.

Species

Macaca mulatta and Macaca fascicularis

Scanner Specifications

• Siemens TIM Trio 3T + AC88 gradient
• Head coil: 8-channel phased-array receive with a single loop transmit

Sample Description

• Sample size: 6
• Species: 5 Macaca mulatta and 1 Macaca fascicularis
• Age distribution: 3-5 years
• Weight distribution: 5.4-7.3 kg
• Sex distribution: All male

Scan Procedures and Parameters

Ethics approval: All animal procedures met the National Institutes of Health Guide for Care and Use of Laboratory Animals, and were approved by the local Institutional Animal Care and Use Committees of The Rockefeller University (protocol number 12585-H) and Weill-Cornell Medical College (protocol number 2010–0029).

Animal care and housing: Pair-housed animals

Any applicable training: none

Scanning preparations

Anesthesia procedures: Ketamine (3 mg/kg) and dexmedetomidine hydrochloride induction (0.02 mg/kg). Maintenance anesthesia: isoflurane (0.5%-0.6%)

Time between anesthesia and scanning: Monkeys were placed in the scanner as soon as isoflurane anesthesia was initiated and stable

Head fixation: Head-post attached to an acrylic headcap

Position in scanner and procedure used: Sphinx position

Contrast agent: IV ferumoxytol (8–10 mg per kg of body weight)

During scanning

Physiological monitoring: Electrocardiogram (sampling rate 400 Hz) and breathing rate (sampling rate 50 Hz)

Additional procedures:

Scan sequences

• Resting-state:
  • Voxel resolution: 1.0 x 1.0 x 1.0 mm
  • TE: 16ms
  • TR: 2000ms
  • Effective Echo Spacing: 0.63ms
  • Phase Encoding Direction: Encoded in columns (COL)
• Field map:
  • Case1: Phase difference image and at least one magnitude image
  • EchoTime1: 2.75
  • EchoTime2: 5.21
  • IntendedFor: EPI distortion correction
• Structural T1:
  • MPRAGE Sequence
  • Voxel resolution: 0.5 x 0.5 x 0.5 mm
  • TE: 2.95ms
  • TR: 2300ms
  • TI: 1100ms
  • Flip angle: 8°

Detailed scanner information from the console is available for resting-state, field map, and structural data.

Publications

• Schwiedrzik, C. M., Zarco, W., Everling, S., & Freiwald, W. A. (2015). Face patch resting state networks link face processing to social cognition. PLoS biology, 13(9), e1002245.

Personnel

• Caspar M. Schwiedrzik
• Winrich Freiwald
• Wilbert Zarco

Acknowledgements

We would like to thank M. Borisov for the development of the stimulus control software (Visiko). S. Rasmussen and A. Gonzalez for expert veterinary and technical care.

Funding

This work was supported by:

• A Human Frontier Science Program Long-Term Fellowship (LT001118/2012-L, CMS)
• The National Institutes of Health (F05 MH094113, WZ)
• An Irma T. Hirschl/Monique Weill-Caulier Trusts Award (WAF)
• A Pew Scholar Award in the Biomedical Sciences (WAF)
• A McKnight Scholars Award (WAF)
• A Human Frontier Science Program Research Grant (RGP0015/2013, WAF)
• The New York Stem Cell Foundation (NYSCF-R-NI23, WAF)
• The National Eye Institute (R01 EY021594, WAF)
• The National Institute of Mental Health (R01 MH105397, WAF)
• The NSF Science and Technology Center for Brains, Minds, and Machines (CCF-1231216/5710003506, WAF)
• The National Science Foundation (INSPIRE Track 2 DBI-1343174, WAF).

WZ is a Pew Latin American Fellow (2010-000225-010). WAF is a New York Stem Cell Foundation-Robertson Investigator. CMS is currently supported by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 706519

Downloads

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